Category Archives: Transcription Modeling

Protected: hb variability figs

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Protected: shadow modeling

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Protected: enhancer gradient analysis (hb + sna)

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Transcription modeling

Some thoughts on simple transcription models. Best case: noise is Poisson — limited only by the arrival of a single rate limiting component.  This allows for only linear control: doubling activator doubles arrival rate of transcription machinery. Adding opening and … Continue reading

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Protected: Transcription kinetics

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Analyzing effect of increasing Gal4

Images with high variability have high overall average expression rate in MGa2x, images with more uniform expression have lower levels.  The reverse is true for MGa1x. MGa1x          

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Protected: Comparing tiling data to counting data

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Transcription discussions

Notes on Transcription modeling: need to be careful with discrete nature of Poisson cdf — incomplete gamma functions are not discrete, can’t throw away the floor function.  So you do need to wait at least until you have 1 bcd … Continue reading

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Protected: hb-enhancer modeling cont pt2

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Protected: hb enhancer modeling cont…

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