Category Archives: Transcription Modeling

Protected: enhancer modeling

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extending enhancer modeling to snail data

Variation in activation state among cells is uniformly 10 fold larger in all data samples than expected by binomial statistics (independent cellular response with fixed probability) Maybe we need to correct for borders, because the vast majority of these missing … Continue reading

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Coding

Downloading scipy to facilitate migrating simulation of code into python. Some trouble-shooting, but it works fine now:

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Protected: Modeling hb-shadow data

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writing

Continuing work on manuscript draft “Effect of binding site number…” (Bicoid_limits_paper.tex).  Moved to dropbox folder for easy multi-site editing.

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writing

Working on text and figures for “Effect of binding site number and spacing on transcription regulation” MS. General outline: Recap key conclusions from Gregor and Dostatni papers. Motivate developing a method for relating transcriptional activity to limits in concentration (integrated … Continue reading

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Protected: hb enhancer modeling

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Comparison to Gregor data

To count all 770 molecules in the nucleus according to Thomas data (D =1, c=4.8, a=.003) would take 890 minutes (and give 3.6% diffusion error). naturally 100 molecules gives a std/mean 0f 10%, and is thus the natural threshold for … Continue reading

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Protected: Comparison to hb data

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Protected: Transcription modeling hb activation

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