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Category Archives: Transcription Modeling
Protected: enhancer modeling
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extending enhancer modeling to snail data
Variation in activation state among cells is uniformly 10 fold larger in all data samples than expected by binomial statistics (independent cellular response with fixed probability) Maybe we need to correct for borders, because the vast majority of these missing … Continue reading
Coding
Downloading scipy to facilitate migrating simulation of code into python. Some trouble-shooting, but it works fine now:
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Protected: Modeling hb-shadow data
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writing
Continuing work on manuscript draft “Effect of binding site number…” (Bicoid_limits_paper.tex). Moved to dropbox folder for easy multi-site editing.
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writing
Working on text and figures for “Effect of binding site number and spacing on transcription regulation” MS. General outline: Recap key conclusions from Gregor and Dostatni papers. Motivate developing a method for relating transcriptional activity to limits in concentration (integrated … Continue reading
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Protected: hb enhancer modeling
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Comparison to Gregor data
To count all 770 molecules in the nucleus according to Thomas data (D =1, c=4.8, a=.003) would take 890 minutes (and give 3.6% diffusion error). naturally 100 molecules gives a std/mean 0f 10%, and is thus the natural threshold for … Continue reading
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Protected: Comparison to hb data
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Protected: Transcription modeling hb activation
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