Sunday 10/04/15

exploring tSNE (11 am -3:50 pm)

  • looking at L7 data
  • see the expected correlations (here in 3D)
    tSNE_3D_geneCorrelation
  • can also see dataset biases (these go away on z-normalization).
    tSNE_by_cell_coloredByDataset
    tSNE_by_cell_znormData_colorByDataset
  • 1000 gene data
    tSNE_1000gene
  • not so good for chromatin structure yet
    • algorithm cares about absolute orientation (forward and backward slanty 1s are different, 6s and 9s are different).
    • could do some sort of global rotation to fix this, which would rotate all 1s in same direction
    • still wouldn’t capture features likes lots of protrusions — its hierarchical clustering of absolute distances of the measurements.
  • obviously our data descriptors like volume still have interesting affects on the data
    tSNE_data_Properties
    tSNE_on_1000ptXYvectors_largeDomains
    tSNE_data_Properties2
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