Wednesday 03/19/14

10:20a – 11:30p

PH project

Simulations / model description

  • Improved behavior from PH simulation
  • \Data\2014-03-17_PhSim\PhCell_CappingModel4

lowVhighPHmut2

PHmutClusterWithFree

phMclusterEffects

lowVhighPHmut

Main Figures

  • wrote new scripts to graph the data in figures 1-3 quickly. Useful for changing binning intervals, fonts / colors / sizes etc easily.
  • updated figures 1-3 to match new layout requests, fix match true-black, make scalebars equal width, match fontsizes, match panel spacing, correct cropping etc.
  • sent new figures to Ajaz.
  • BK currently reviewing manuscript.

Oligo-Secondaries

  • working on figure
  • wrote caption for current figure draft
  • emailed draft and caption to Ting and Brian

Computer upgrades

  • discussed windows server upgrades with CDW rep
  • Ordered windows server updates
  • need quote for server (can get remote desktop licenses through HHMI CDW portal).
  • requested new quote with HHMI as bill to.
  • configured remote desktop timeouts on cajal: http://technet.microsoft.com/en-us/library/cc754272.aspx
    • disconnected state: 5 days until termination
    • idle state: 2 days until disconnect

Chromatin Project

  • set-up PCRs for probe making
  • PCRs work (old get not so good and a bit overloaded). Some high MW product.
  • also most samples mostly bubble band — expect 122 bp. Some samples have some low MW product, I wonder if this is mispriming? Should sequence this library too (MiSeq kit on the way).
  • ran gel cleanup.
  • set up T7 reactions to run O/N with RNasin inhibitor. Run started ~10:00p.

lib3_C01-08pcr_Gels

Data Analysis

  • running bead-data compression for recently split multi-color data.
  • Attempt resuming F12F11 data. Still missing 647 data for image 2. Now analyzing.
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