Sunday 06/02/13

10:00 A – 8:00 P

Ph-FLAG analysis / clustering

  • Blocking total counts per cell (after applying mask) results in good comparison. Currently 50-300K: window probably a bit large but need to get the cell numbers up.
  • Ph wt data: Buffer didn’t last too well? some cells look over-dried maybe? Should repeat.
  • Ph-M flag: two data sets look good
  • Ph-wt-flag: didn’t image enough frames to make quantitative comparison to previous data set (50K vs 120K frames).

Ph-FLAG planning

  • reagents for Ajaz.
  • set up to stain mutant, wt, and s2 cells all with wt Ph. use 488 to mark transformants.
  • wt-ph embryo staining

STORM

  • what’s the additional slider under the objective do? When did this get added to the beam path?
  • All quadview images from all color channels are getting mapped to the 647 corner. Why? This makes it very difficult to take bead movies appropriately…
  • spent 2 hours so far trying to get 750 to image appropriately
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